Pub. Date : 2005 May
PMID : 15867854
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | A screening of various factors (histamine, IFN-gamma, IL-1beta, IL-2, IL-3, IL-4, IL-5, IL-8, IL-12, and TNF-alpha) identified IFN-gamma as a potent factor capable of reducing epithelial barrier properties and enhancing transepithelial allergen penetration. | Histamine | interferon gamma | Homo sapiens |
2 | Increased submucosal allergen concentrations caused by IFN-gamma-mediated reduction of epithelial barrier function provoked a more than 7-fold augmentation of histamine release from sensitized basophils. | Histamine | interferon gamma | Homo sapiens |