Pub. Date : 2005
PMID : 15867196
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A reduction in XRCC1 protein levels resulted in decreased SSBR capacity as measured by the comet assay and intracellular NAD(P)H levels, hypersensitivity to the cell killing effects of the DNA damaging agents methyl methanesulfonate (MMS), hydrogen peroxide and ionizing radiation and enhanced formation of micronuclei following exposure to MMS. | Methyl Methanesulfonate | X-ray repair cross complementing 1 | Homo sapiens |
| 2 | A reduction in XRCC1 protein levels resulted in decreased SSBR capacity as measured by the comet assay and intracellular NAD(P)H levels, hypersensitivity to the cell killing effects of the DNA damaging agents methyl methanesulfonate (MMS), hydrogen peroxide and ionizing radiation and enhanced formation of micronuclei following exposure to MMS. | Methyl Methanesulfonate | X-ray repair cross complementing 1 | Homo sapiens |
| 3 | A reduction in XRCC1 protein levels resulted in decreased SSBR capacity as measured by the comet assay and intracellular NAD(P)H levels, hypersensitivity to the cell killing effects of the DNA damaging agents methyl methanesulfonate (MMS), hydrogen peroxide and ionizing radiation and enhanced formation of micronuclei following exposure to MMS. | Methyl Methanesulfonate | X-ray repair cross complementing 1 | Homo sapiens |
| 4 | Lowered XRCC1 protein levels were also associated with a significant delay in S-phase progression after exposure to MMS. | Methyl Methanesulfonate | X-ray repair cross complementing 1 | Homo sapiens |