Pub. Date : 2005 Sep
PMID : 15860639
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Further examination showed that DFMO pretreatment inhibited the radiation-induced increase in the proapoptotic protein Bax. | Eflornithine | BCL2 associated X, apoptosis regulator | Rattus norvegicus |
| 2 | We conclude that polyamine depletion by DFMO inhibits gamma-irradiation-induced apoptosis of intestinal epithelial cells both in vitro and in vivo through inhibition of Bax and caspase-3 activity, which leads to attenuation of radiation-inflicted intestinal injury. | Eflornithine | BCL2 associated X, apoptosis regulator | Rattus norvegicus |