Title : Calcium channel blocker class heterogeneity: select aspects of pharmacokinetics and pharmacodynamics.

Pub. Date : 2005 Apr

PMID : 15858399






2 Functional Relationships(s)
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Protein Name
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1 CCBs are both substrates for, and in the instance of verapamil and diltiazem inhibitors of, cytochrome P450 3A4. Diltiazem cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 In the case of verapamil and diltiazem, this inhibitory effect increases the likelihood of drug-drug interactions with other compounds similarly metabolized by cytochrome P450 3A4. Diltiazem cytochrome P450 family 3 subfamily A member 4 Homo sapiens