Title : Poly (adp-ribose) polymerase inhibitors as potential therapeutic agents in stroke and neurotrauma.

Pub. Date : 2005 Apr

PMID : 15857303






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Upon binding to DNA breaks, activated PARP cleaves NAD+ into nicotinamide and ADP-ribose and polymerizes the latter on nuclear acceptor proteins including histones, transcription factors and PARP itself. Niacinamide poly(ADP-ribose) polymerase 1 Homo sapiens
2 Upon binding to DNA breaks, activated PARP cleaves NAD+ into nicotinamide and ADP-ribose and polymerizes the latter on nuclear acceptor proteins including histones, transcription factors and PARP itself. Niacinamide poly(ADP-ribose) polymerase 1 Homo sapiens