Title : Simvastatin attenuates renal inflammation, tubular transdifferentiation and interstitial fibrosis in rats with unilateral ureteral obstruction.

Pub. Date : 2005 Aug

PMID : 15855201






1 Functional Relationships(s)
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1 TGF-beta1, which was highly induced in the obstructed kidneys, decreased at the post-transcriptional level with SIMV treatment (5.35+/-0.75 vs 13.10+/-2.9 OD in VH, P<0.05). Simvastatin transforming growth factor, beta 1 Rattus norvegicus