Title : PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain.

Pub. Date : 2005 May

PMID : 15852009






1 Functional Relationships(s)
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1 Here, we demonstrate a central role for phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)) in the activation of recombinant TRPM8 channels by both cold and menthol. Phosphatidylinositol 4,5-Diphosphate transient receptor potential cation channel subfamily M member 8 Homo sapiens