Pub. Date : 2005 Jul
PMID : 15845907
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | At least 2 distinct pathways generating reactive oxygen species mediate vascular cell adhesion molecule-1 induction by advanced glycation end products. | Reactive Oxygen Species | vascular cell adhesion molecule 1 | Homo sapiens |
| 2 | We investigated the role of distinct sources of ROS, including the mitochondrial electron transport chain, NAD(P)H oxidase, xanthine oxidase, and arachidonic acid metabolism, in AGE-induced VCAM-1 expression. | Reactive Oxygen Species | vascular cell adhesion molecule 1 | Homo sapiens |
| 3 | The inhibition of Cu/Zn superoxide dismutase inhibited both ROS and VCAM-1 induction, indicating that H2O2 by this source is involved as a mediator of VCAM-1 expression by AGEs. | Reactive Oxygen Species | vascular cell adhesion molecule 1 | Homo sapiens |