Title : Identification of cytochrome P450 and arylamine N-acetyltransferase isoforms involved in sulfadiazine metabolism.

Pub. Date : 2005 Jul

PMID : 15843491






1 Functional Relationships(s)
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1 Fluconazole (CYP2C9/19 and CYP3A4 inhibitor at clinical concentrations) inhibited hydroxylamine formation, with one-enzyme model K(i) estimates ranging from 9 to 40 microM. Fluconazole cytochrome P450 family 3 subfamily A member 4 Homo sapiens