Title : Histamine potentiates human platelet aggregation induced by platelet-activating factor.

Pub. Date : 1992

PMID : 1582704






2 Functional Relationships(s)
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1 Using human platelet-rich plasma (PRP) we found that histamine concentration-dependently potentiated platelet aggregation induced by platelet-activating factor (PAF). Histamine PCNA clamp associated factor Homo sapiens
2 Chloropyramine reduced the potentiating effect of histamine on PAF-induced platelet aggregation, and when it was coadministered with BN 52021, inducing 63% inhibition of PAF-induced aggregation, the histamine-potentiated PAF response was completely abolished. Histamine PCNA clamp associated factor Homo sapiens