Title : Role of human cytochrome P450 3A4 in the metabolism of DA-8159, a new erectogenic.

Pub. Date : 2004 Nov-Dec

PMID : 15801542






3 Functional Relationships(s)
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1 The purpose of this paper was to characterize cytochrome P450 (CYP) enzymes involved in N-dealkylation of a new oral erectogenic, DA-8159 to DA-8164, a major circulating active metabolite, in human liver microsomes and to investigate the inhibitory potential of DA-8159 on CYP enzymes. Nitrogen cytochrome P450 family 4 subfamily F member 3 Homo sapiens
2 The purpose of this paper was to characterize cytochrome P450 (CYP) enzymes involved in N-dealkylation of a new oral erectogenic, DA-8159 to DA-8164, a major circulating active metabolite, in human liver microsomes and to investigate the inhibitory potential of DA-8159 on CYP enzymes. Nitrogen cytochrome P450 family 4 subfamily F member 3 Homo sapiens
3 The purpose of this paper was to characterize cytochrome P450 (CYP) enzymes involved in N-dealkylation of a new oral erectogenic, DA-8159 to DA-8164, a major circulating active metabolite, in human liver microsomes and to investigate the inhibitory potential of DA-8159 on CYP enzymes. Nitrogen cytochrome P450 family 4 subfamily F member 3 Homo sapiens