Title : Impact of a soluble phospholipase A2 inhibitor on inhaled allergen challenge in subjects with asthma.

Pub. Date : 2005 Feb

PMID : 15801331






1 Functional Relationships(s)
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1 The possible roles of secretory phospholipases A2 (sPLA2) in asthma include the release of arachidonic acid from cellular membranes, generation of lysophospholipids, sPLA2-mediated activation of cPLA2 with increased leukotriene production, and surfactant degradation. Leukotrienes phospholipase A2 group IVA Homo sapiens