Title : Simvastatin prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced striatal dopamine depletion and protein tyrosine nitration in mice.

Pub. Date : 2005 Mar 10

PMID : 15777746






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The results suggest that simvastatin inhibits the formation of TNF-alpha and peroxynitrite in activated microglia thereby protecting dopaminergic neurons from inflammatory damage. Simvastatin tumor necrosis factor Mus musculus