Title : Potential role of cAMP response element-binding protein in ethanol-induced N-methyl-D-aspartate receptor 2B subunit gene transcription in fetal mouse cortical cells.

Pub. Date : 2005 Jun

PMID : 15774772






5 Functional Relationships(s)
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1 Potential role of cAMP response element-binding protein in ethanol-induced N-methyl-D-aspartate receptor 2B subunit gene transcription in fetal mouse cortical cells. Ethanol cAMP responsive element binding protein 1 Mus musculus
2 We find a significant increase in phosphorylated CREB, without change in total CREB protein, in cells treated with ethanol for 5 days. Ethanol cAMP responsive element binding protein 1 Mus musculus
3 We find a significant increase in phosphorylated CREB, without change in total CREB protein, in cells treated with ethanol for 5 days. Ethanol cAMP responsive element binding protein 1 Mus musculus
4 CREB phosphorylation was increased by ethanol treatment in both media, irrespective of the presence of serum. Ethanol cAMP responsive element binding protein 1 Mus musculus
5 Our results indicate that CREB is probably involved in mediating ethanol-induced up-regulation of NR2B gene. Ethanol cAMP responsive element binding protein 1 Mus musculus