Title : Influence of itraconazole co-administration and CYP2D6 genotype on the pharmacokinetics of the new antipsychotic ARIPIPRAZOLE.

Pub. Date : 2005 Feb

PMID : 15770075






1 Functional Relationships(s)
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1 The urinary 6beta-hydroxycortisol/cortisol concentration ratio following ITZ administration for 7 consecutive days was about half of that before the start of ITZ administration, indicating that CYP3A4 metabolic activity was inhibited by administration of ITZ. 6 beta-hydroxycortisol cytochrome P450 family 3 subfamily A member 4 Homo sapiens