Title : A mutant of eukaryotic protein synthesis initiation factor eIF4E(K119A) has an increased binding affinity for both m7G cap analogues and eIF4G peptides.

Pub. Date : 2005 Mar 22

PMID : 15766285






2 Functional Relationships(s)
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1 The temperature-dependent K(d) values for cap analogues were markedly lower, indicating tighter binding, with the eIF4E(K119A) mutant compared with wild-type eIF4E. cap eukaryotic translation initiation factor 4E Homo sapiens
2 The temperature-dependent K(d) values for cap analogues were markedly lower, indicating tighter binding, with the eIF4E(K119A) mutant compared with wild-type eIF4E. cap eukaryotic translation initiation factor 4E Homo sapiens