Pub. Date : 2005 Apr 1
PMID : 15763541
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Dual effects of acetylsalicylic acid on mast cell degranulation, expression of cyclooxygenase-2 and release of pro-inflammatory cytokines. | Aspirin | prostaglandin-endoperoxide synthase 2 | Homo sapiens |
| 2 | ASA blocked the expression of cyclooxygenase-2, the production of tumor necrosis factor-alpha and interleukin-6, and the release of granule mediators from mast cells in a concentration-dependent fashion. | Aspirin | prostaglandin-endoperoxide synthase 2 | Homo sapiens |
| 3 | Interestingly, the expression of cyclooxygenase-2 was not inhibited at 1mM ASA, but was even enhanced significantly. | Aspirin | prostaglandin-endoperoxide synthase 2 | Homo sapiens |