Title : [Expressions of 8-OH-dG, k-ras, and p53 genes in pleural effusion cells and their clinical significances].

Pub. Date : 2005 Mar

PMID : 15757539






1 Functional Relationships(s)
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1 8-hydoxy-2deoxy-guanosine (8-OH-dG), a biomarker of oxidative DNA damage, plays important roles in initiation, progression, and prognosis of lung cancer, and closely relates with mutations of k-ras and p53 genes in carcinogenesis of lung tissue. 8-hydoxy-2deoxy-guanosine tumor protein p53 Homo sapiens