Title : [Expressions of 8-OH-dG, k-ras, and p53 genes in pleural effusion cells and their clinical significances].

Pub. Date : 2005 Mar

PMID : 15757539






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 8-hydoxy-2deoxy-guanosine (8-OH-dG), a biomarker of oxidative DNA damage, plays important roles in initiation, progression, and prognosis of lung cancer, and closely relates with mutations of k-ras and p53 genes in carcinogenesis of lung tissue. 8-ohdg tumor protein p53 Homo sapiens
2 Rank correlation analysis showed that protein expression of 8-OH-dG positively correlated with those of k-ras (RS=0.643, P < 0.01), and p53 (RS=0.827, P < 0.01)u protein expression of k-ras positively correlated with that of p53 (RS=0.897, P < 0.01). 8-ohdg tumor protein p53 Homo sapiens
3 Rank correlation analysis showed that protein expression of 8-OH-dG positively correlated with those of k-ras (RS=0.643, P < 0.01), and p53 (RS=0.827, P < 0.01)u protein expression of k-ras positively correlated with that of p53 (RS=0.897, P < 0.01). 8-ohdg tumor protein p53 Homo sapiens