Title : Stem cell factor has a suppressive activity to IgE-mediated chemotaxis of mast cells.

Pub. Date : 2005 Mar 15

PMID : 15749900






3 Functional Relationships(s)
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1 Although BMCMC and HuCMC sensitized with IgE directly moved toward specific Ag, preincubation for even 1 h with an optimal dose of SCF suppressed the IgE-mediated chemotactic movement. bmcmc kit ligand Mus musculus
2 In contrast, preincubation of BMCMC and HuCMC with SCF enhanced beta-hexosaminidase release and Ca2+ mobilization in response to Ag after sensitization with IgE. bmcmc kit ligand Mus musculus
3 Using the real-time record of chemotactic migration, BMCMC preincubated with SCF manifested motionless without degranulation. bmcmc kit ligand Mus musculus