Title : Phase I study of MetXia-P450 gene therapy and oral cyclophosphamide for patients with advanced breast cancer or melanoma.

Pub. Date : 2005 Feb 15

PMID : 15746054






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Cytochrome P450 enzymes are primarily expressed in the liver and convert the prodrug cyclophosphamide to an active phosphoramide mustard and acrolein. Acrolein cytochrome P450 family 4 subfamily F member 3 Homo sapiens