Title : A MEK inhibitor (U0126) markedly inhibits direct liver invasion of orthotopically inoculated human gallbladder cancer cells in nude mice.

Pub. Date : 2004 Dec

PMID : 15743030






1 Functional Relationships(s)
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1 MEK inhibitors (PD98059 and U0126) inhibited the production of MMP-2, MMP-9 and high MW uPA, and upregulated TIMPs (TIMP-1, TIMP-2 and TIMP-3). U 0126 matrix metallopeptidase 9 Mus musculus