Title : The production of IL-1 receptor antagonist in IFN-beta-stimulated human monocytes depends on the activation of phosphatidylinositol 3-kinase but not of STAT1.

Pub. Date : 2005 Mar 1

PMID : 15728510






1 Functional Relationships(s)
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1 Although both inhibitors of PI3K and MEK1 diminished the Ser(727) phosphorylation of STAT1 induced by IFN-beta, only Ly294002 inhibited sIL-1Ra production. Serine interferon beta 1 Homo sapiens