Title : Diuretic and non-diuretic actions of furosemide: effects of probenecid.

Pub. Date : 1992 Feb

PMID : 1572111






3 Functional Relationships(s)
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1 Furosemide causes not only natriuresis, but a rapid (5-10 min) increase in plasma renin activity. Furosemide renin Homo sapiens
2 Drugs like indomethacin abolish the renin increment and could potentially affect both mechanisms: they inhibit cyclooxygenase but could also compete with furosemide for transport into the tubular lumen, reducing furosemide concentration at its site of action. Furosemide renin Homo sapiens
3 Drugs like indomethacin abolish the renin increment and could potentially affect both mechanisms: they inhibit cyclooxygenase but could also compete with furosemide for transport into the tubular lumen, reducing furosemide concentration at its site of action. Furosemide renin Homo sapiens