Title : FK1706, a novel non-immunosuppressive immunophilin: neurotrophic activity and mechanism of action.

Pub. Date : 2005 Feb 10

PMID : 15713424






1 Functional Relationships(s)
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1 FK1706, a derivative of FK506, showed similarly high affinity for two FKBP subtypes, FKBP-12 and FKBP-52, but inhibited T-cell proliferation and interleukin-2 cytokine production with much lower potency and efficacy than FK506. Tacrolimus FKBP prolyl isomerase 4 Homo sapiens