Title : Enniatin has a new function as an inhibitor of Pdr5p, one of the ABC transporters in Saccharomyces cerevisiae.

Pub. Date : 2005 Mar 25

PMID : 15707993






2 Functional Relationships(s)
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1 A non-toxic concentration of each enniatin (5 microg/ml, approximately 7.8 microM) strongly inhibited a Pdr5p-mediated efflux of cycloheximide or cerulenin in Pdr5p-overexpressing cells. Cycloheximide ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C
2 A non-toxic concentration of each enniatin (5 microg/ml, approximately 7.8 microM) strongly inhibited a Pdr5p-mediated efflux of cycloheximide or cerulenin in Pdr5p-overexpressing cells. Cycloheximide ATP-binding cassette multidrug transporter PDR5 Saccharomyces cerevisiae S288C