Title : POB1 over-expression inhibits RLIP76-mediated transport of glutathione-conjugates, drugs and promotes apoptosis.

Pub. Date : 2005 Mar 25

PMID : 15707977






1 Functional Relationships(s)
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1 Both doxorubicin and a model GSH-conjugate, dinitrophenyl-S-glutathione (DNP-SG), transport were inhibited by POB1 in a concentration-dependent manner but not by POB1(1-512), lacking RLIP76-binding site. S-(2,4-dinitrophenyl)glutathione RALBP1 associated Eps domain containing 2 Homo sapiens