Title : Proteasome inhibitors induce peroxisome proliferator-activated receptor transactivation through RXR accumulation and a protein kinase C-dependent pathway.

Pub. Date : 2005 Mar 10

PMID : 15707588






1 Functional Relationships(s)
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1 In this study, using luciferase assay of a reporter gene containing PPAR response element (PPRE), we found PPRE transactivity was additively induced by PPAR gamma activator (15dPGJ2) and RXR activator (9-cis retinoic acid, 9-cis RA). Tretinoin retinoid X receptor alpha Homo sapiens