Title : A novel localization of the G-protein-coupled CysLT1 receptor in the nucleus of colorectal adenocarcinoma cells.

Pub. Date : 2005 Feb 1

PMID : 15705869






1 Functional Relationships(s)
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1 Searching for a link between inflammation and colon cancer, we have found that the inflammatory mediator leukotriene D(4) (LTD(4)), via its receptor CysLT(1), induces cyclooxygenase-2 expression, survival, and proliferation in intestinal epithelial cells. Leukotrienes prostaglandin-endoperoxide synthase 2 Homo sapiens