Title : Implication of phospholipase D2 in oxidant-induced phosphoinositide 3-kinase signaling via Pyk2 activation in PC12 cells.

Pub. Date : 2005 Apr 22

PMID : 15705590






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 H(2)O(2)-induced phosphorylation of Akt and p70S6K was dependent on phosphatidylinositol 3-kinase (PI3K) activity and was abolished by 1-butanol but not t-butanol. Hydrogen Peroxide AKT serine/threonine kinase 1 Rattus norvegicus
2 Furthermore, the PI3K/Akt activation in response to H(2)O(2) was reduced by transfection of either PLD2KR or the dominant negative Pyk2DN. Hydrogen Peroxide AKT serine/threonine kinase 1 Rattus norvegicus