Title : Meldrum's acids as acylating agents in the catalytic intramolecular Friedel-Crafts reaction.

Pub. Date : 2005 Feb 18

PMID : 15704966






1 Functional Relationships(s)
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1 This method was further applied to the synthesis of 1-tetralones, 1-benzosuberones, and the potent acetylcholinesterase inhibitor donepezil. Donepezil acetylcholinesterase (Cartwright blood group) Homo sapiens