Pub. Date : 2005 May
PMID : 15703382
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Expression of the retinoic acid-metabolizing enzyme CYP26A1 limits programmed cell death. | Tretinoin | cytochrome P450 family 26 subfamily A member 1 | Homo sapiens |
| 2 | On the other hand, we show here that various cell lines overexpressing CYP26A1, a cytochrome P450 enzyme specifically involved in the catabolic inactivation of RA, exhibit increased resistance to various apoptogenic factors, including death receptor ligands such as tumor necrosis factor-related apoptosis-inducing ligand. | Tretinoin | cytochrome P450 family 26 subfamily A member 1 | Homo sapiens |