Pub. Date : 2005 Jun
PMID : 15695555
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Although RT-PCR demonstrated the presence of equilibrative nucleoside transporter-1 (ENT-1) and ENT-2 mRNA, functional studies revealed that adenosine transport in HASMCs was predominantly mediated by ENT-1 and inhibited by nitrobenzylmercaptopurine riboside (NBMPR, IC(50) = 0.69 +/- 0.05 nM). | Adenosine | solute carrier family 29 member 1 (Augustine blood group) | Homo sapiens |
2 | Pathologically, the increase in ENT-1 activity in diabetes may affect the availability of adenosine in the vicinity of adenosine receptors and, thus, alter vascular functions in diabetes. | Adenosine | solute carrier family 29 member 1 (Augustine blood group) | Homo sapiens |