Title : Interferon gamma induces neurite outgrowth by up-regulation of p35 neuron-specific cyclin-dependent kinase 5 activator via activation of ERK1/2 pathway.

Pub. Date : 2005 Apr 1

PMID : 15695523






1 Functional Relationships(s)
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1 IFN-gamma-induced neurite outgrowth was abolished by the treatment of MEK1/2 kinase inhibitors, such as U0126 and PD98059, which inhibit the ERK1/2 activation and subsequently prevent the up-regulation of p35 expression and Cdk5 activity. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one cyclin dependent kinase 5 Homo sapiens