Title : Gene expression profiling in conjunction with physiological rescues of IKKalpha-null cells with wild type or mutant IKKalpha reveals distinct classes of IKKalpha/NF-kappaB-dependent genes.

Pub. Date : 2005 Apr 8

PMID : 15695520






1 Functional Relationships(s)
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1 To prove that the kinase activity of IKKalpha was required on a genomic scale, the same physiological rescue was performed with a kinase-dead, ATP binding domain IKKalpha mutant (IKKalpha(K44M)). Adenosine Triphosphate conserved helix-loop-helix ubiquitous kinase Mus musculus