Title : Alpha,beta-unsaturated ketone is a core moiety of natural ligands for covalent binding to peroxisome proliferator-activated receptor gamma.

Pub. Date : 2005 Apr 8

PMID : 15695504






1 Functional Relationships(s)
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1 Screening of lipid metabolites containing the alpha,beta-unsaturated ketone revealed that several other oxidized metabolites of hydroxyeicosatetraenoic acid, hydroxyeicosadecaenoic acid, and prostaglandins can also function as novel covalent ligands for PPARgamma. Prostaglandins peroxisome proliferator activated receptor gamma Homo sapiens