Title : The negative immunoregulatory effects of fluoxetine in relation to the cAMP-dependent PKA pathway.

Pub. Date : 2005 Mar

PMID : 15683856






1 Functional Relationships(s)
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1 Since cyclic adenosine monophosphate (cAMP) production is stimulated by some antidepressants, and since cAMP inhibits IFN-gamma and stimulates IL-10 production, we postulate that the negative immunoregulatory effects of antidepressants result from their effects on the cAMP-dependent protein kinase A (PKA) pathway. Cyclic AMP interleukin 10 Homo sapiens