Title : Rescue of early-stage myelodysplastic syndrome-deriving erythroid precursors by the ectopic expression of a dominant-negative form of FADD.

Pub. Date : 2005 May 15

PMID : 15677568






1 Functional Relationships(s)
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1 These results extend the observation that Fas-dependent activation of caspase-8 accounts for apoptosis of early stage MDS erythroid cells and demonstrate for the first time that FADD is a valuable target to correct ineffective erythropoiesis in these syndromes. ammonium ferrous sulfate caspase 8 Homo sapiens