Title : Expanded polyglutamine peptides disrupt EGF receptor signaling and glutamate transporter expression in Drosophila.

Pub. Date : 2005 Mar 1

PMID : 15677486






5 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Huntington"s disease (HD) is a late onset heritable neurodegenerative disorder caused by expansion of a polyglutamine (polyQ) sequence in the protein huntingtin (Htt). polyglutamine huntingtin Drosophila melanogaster
2 Huntington"s disease (HD) is a late onset heritable neurodegenerative disorder caused by expansion of a polyglutamine (polyQ) sequence in the protein huntingtin (Htt). polyglutamine huntingtin Drosophila melanogaster
3 Huntington"s disease (HD) is a late onset heritable neurodegenerative disorder caused by expansion of a polyglutamine (polyQ) sequence in the protein huntingtin (Htt). polyglutamine huntingtin Drosophila melanogaster
4 Huntington"s disease (HD) is a late onset heritable neurodegenerative disorder caused by expansion of a polyglutamine (polyQ) sequence in the protein huntingtin (Htt). polyglutamine huntingtin Drosophila melanogaster
5 We targeted the expression of the polyQ-containing domain of Htt or an extended polyQ peptide alone in a subset of Drosophila glial cells, where the only fly glutamate transporter, dEAAT1, is detected. polyglutamine huntingtin Drosophila melanogaster