Title : Apoptosis of hematopoietic cells induced by growth factor withdrawal is associated with caspase-9 mediated cleavage of Raf-1.

Pub. Date : 2005 Feb 24

PMID : 15674327






1 Functional Relationships(s)
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1 Moreover, Bcl-2 overexpression or treatment with the caspase inhibitor z-VAD.fmk completely prevented Raf-1 cleavage, whereas caspase inhibition by treatment of cells with Ac-DEVD.fmk or z-IETD.fmk, or CrmA overexpression had no effect. FMK v-raf-leukemia viral oncogene 1 Mus musculus