Title : Dipyridamole selectively inhibits inflammatory gene expression in platelet-monocyte aggregates.

Pub. Date : 2005 Feb 8

PMID : 15668340






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Dipyridamole but not aspirin attenuated nuclear translocation of NF-kappaB and blocked the synthesis of MCP-1 at the transcriptional level. Dipyridamole C-C motif chemokine ligand 2 Homo sapiens
2 Dipyridamole also blocked MCP-1 and MMP-9 generated by lipopolysaccharide-treated monocytes, indicating that at least part of its inhibitory action is unrelated to its antiplatelet properties. Dipyridamole C-C motif chemokine ligand 2 Homo sapiens