Title : Induction of CYP1A1 and CYP1B1 in liver and lung by benzo(a)pyrene and 7,12-d imethylbenz(a)anthracene do not affect distribution of polycyclic hydrocarbons to target tissue: role of AhR and CYP1B1 in bone marrow cytotoxicity.

Pub. Date : 2005 Feb 1

PMID : 15667830






2 Functional Relationships(s)
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1 Induction of CYP1A1 and CYP1B1 in liver and lung by benzo(a)pyrene and 7,12-d imethylbenz(a)anthracene do not affect distribution of polycyclic hydrocarbons to target tissue: role of AhR and CYP1B1 in bone marrow cytotoxicity. Benzo(a)pyrene cytochrome P450, family 1, subfamily b, polypeptide 1 Mus musculus
2 Effective delivery of BP to BM is indicated by formation of BP-quinone DNA adducts and the effective induction of CYP1B1. Benzo(a)pyrene cytochrome P450, family 1, subfamily b, polypeptide 1 Mus musculus