Title : Continuous infusion interleukin-2 and antihistamines in melanoma: a retrospective review showing activity of this combination.

Pub. Date : 2004 Dec

PMID : 15665623






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1 Because antihistamines such as cimetidine and ranitidine are commonly used as prophylaxis against gastrointestinal toxicity commonly seen with IL-2, and, because antihistamines may increase natural killer cell activity, it is reasonable to examine the response rate for this combination. Ranitidine interleukin 2 Homo sapiens