Pub. Date : 2005 Feb 1
PMID : 15665077
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | It was found that exposure to the neurotrophin BDNF increased the amplitude of the "GABA currents" (currents elicited by GABA) generated by the epileptic receptors and decreased their run-down; both events being blocked by K252A, a neurotrophin tyrosine kinase receptor B inhibitor. | gamma-Aminobutyric Acid | brain derived neurotrophic factor | Homo sapiens |
2 | It was found that exposure to the neurotrophin BDNF increased the amplitude of the "GABA currents" (currents elicited by GABA) generated by the epileptic receptors and decreased their run-down; both events being blocked by K252A, a neurotrophin tyrosine kinase receptor B inhibitor. | gamma-Aminobutyric Acid | brain derived neurotrophic factor | Homo sapiens |
3 | However, staurosporine (a broad spectrum PK inhibitor), bisindolylmaleimide I (a PKC inhibitor), and U73122 (a phospholipase C inhibitor) blocked the BDNF-induced effects on the epileptic GABA currents. | gamma-Aminobutyric Acid | brain derived neurotrophic factor | Homo sapiens |