Title : Simvastatin attenuates vascular leak and inflammation in murine inflammatory lung injury.

Pub. Date : 2005 Jun

PMID : 15665042






1 Functional Relationships(s)
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1 LPS-mediated lung gene expression was significantly modulated by simvastatin within a number of gene ontologies (e.g., inflammation and immune response, NF-kappaB regulation) and with respect to individual genes implicated in the development or severity of ALI (e.g., IL-6, Toll-like receptor 4). Simvastatin interleukin 6 Mus musculus