Title : Chronic exposure to high glucose impairs bradykinin-stimulated nitric oxide production by interfering with the phospholipase-C-implicated signalling pathway in endothelial cells: evidence for the involvement of protein kinase C.

Pub. Date : 2004 Dec

PMID : 15662551






1 Functional Relationships(s)
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1 Moreover, bradykinin-induced formation of Ins(1,4,5)P(3), a phospholipase C product leading to increases in [Ca(2+)](i), was also inhibited following high glucose culture. ins(1,4,5)p kininogen 1 Bos taurus