Title : Expression of Bcl-xL in ovarian carcinoma is associated with chemoresistance and recurrent disease.

Pub. Date : 2005 Feb

PMID : 15661210






2 Functional Relationships(s)
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1 We found that Bcl-x(L) expression conferred resistance to chemotherapy-induced apoptosis resulting from treatment with cisplatin, paclitaxel, topotecan, and gemcitabine in vitro. Cisplatin BCL2 like 1 Homo sapiens
2 In a xenograft model, Bcl-x(L) expressing tumors continued to grow following treatment with cisplatin, paclitaxel, topotecan, and gemcitabine, in contrast to control tumors, which disappeared. Cisplatin BCL2 like 1 Homo sapiens