Title : Neuroadaptations of total levels of adenylate cyclase, protein kinase A, tyrosine hydroxylase, cdk5 and neurofilaments in the nucleus accumbens and ventral tegmental area do not correlate with expression of sensitized or tolerant locomotor responses to cocaine.

Pub. Date : 2005 Feb

PMID : 15659224






1 Functional Relationships(s)
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1 Only protein kinase A activity levels were altered by cocaine treatment, but this alteration persisted for only 7 days, whereas a sensitized locomotor response was still evident at 21 days. Cocaine protein kinase cAMP-activated catalytic subunit alpha Rattus norvegicus