Title : Protein phosphatase 2A activity associated with Golgi membranes during the G2/M phase may regulate phosphorylation of ERK2.

Pub. Date : 2005 Mar 25

PMID : 15654082






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 ERK proteins are activated exclusively by MAPK kinase 1 and 2 phosphorylation of threonine and tyrosine residues located within the conserved TXY MAPK activation motif. Threonine mitogen-activated protein kinase 1 Homo sapiens
2 Although dual phosphorylation of Thr and Tyr residues confers full activation of ERK, in vitro studies suggest that a single phosphorylation on either Thr or Tyr may yield partial ERK activity. Threonine mitogen-activated protein kinase 1 Homo sapiens
3 Although dual phosphorylation of Thr and Tyr residues confers full activation of ERK, in vitro studies suggest that a single phosphorylation on either Thr or Tyr may yield partial ERK activity. Threonine mitogen-activated protein kinase 1 Homo sapiens