Title : Mechanisms involved in spironolactone-induced choleresis in the rat. Role of multidrug resistance-associated protein 2.

Pub. Date : 2005 Feb 1

PMID : 15652244






2 Functional Relationships(s)
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1 Enhanced activity and expression of Mrp2 was confirmed by analyzing the excretion rate of dinitrophenyl S-glutathione, an exogenous substrate of Mrp2, in isolated hepatocytes and by immunofluorescence microscopy, respectively. S-(2,4-dinitrophenyl)glutathione ATP binding cassette subfamily C member 2 Rattus norvegicus
2 Enhanced activity and expression of Mrp2 was confirmed by analyzing the excretion rate of dinitrophenyl S-glutathione, an exogenous substrate of Mrp2, in isolated hepatocytes and by immunofluorescence microscopy, respectively. S-(2,4-dinitrophenyl)glutathione ATP binding cassette subfamily C member 2 Rattus norvegicus